cyproterone acetate造句

• It also shows some glucocorticoid activity similarly to cyproterone acetate and unesterified cyproterone.
• Some examples of widely used and highly-potent antiandrogens include cyproterone acetate and bicalutamide.
• So-called brake drugs, such as cyproterone acetate, can retard adolescence.
• Several reports also state that cyproterone acetate causes liver hyperplasia.
• The binding affinity of oxendolone for the AR is far lower than that of cyproterone acetate.
• Cyproterone acetate was developed to overcome this problem.
• Unlike the related drug cyproterone acetate, MPA does not appear to be associated with vitamin B12 deficiency.
• Among others, this class of drugs includes chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, medroxyprogesterone acetate, and megestrol acetate.
• However, antigonadotropic antiandrogens like cyproterone acetate can produce hypoestrogenism, amenorrhea, and osteoporosis in women, among other side effects.
• Cyproterone acetate is the most commonly used antiandrogen, except in the United States, where it may not be available.
• "' Edogestrone "'( antagonizes it, displacing androgens like testosterone from the receptor, though not as potently as cyproterone acetate.
• Progestogens that are used as antigonadotropins include chlormadinone acetate, cyproterone acetate, gestonorone caproate, medroxyprogesterone acetate, megestrol acetate, and oxendolone.
• These NSAAs eventually crossed the blood brain barrier, like cyproterone acetate, leading to a subsequent increase in serum testosterone levels.
• Similar poor results with the topical route have disappointingly been found for other antiandrogens such as cyproterone acetate and spironolactone.
• Cyproterone acetate acts both directly as an antiandrogen in prostate cancer cells and also functions to indirectly decrease serum testosterone levels.
• They are also sometimes used as superior alternatives to anti-androgens like spironolactone and cyproterone acetate for suppressing testosterone production in trans women.
• These include, to varying extents, cyproterone acetate, flutamide, nilutamide, bicalutamide, aminoglutethimide, and ketoconazole . and other antiandrogens are not associated with hepatotoxicity.
• Systemically, it is treated with antiandrogens such as cyproterone acetate, flutamide and spironolactone to control the androgen levels in the patient's body.
• Cyproterone acetate has a dual mode of action as it competes directly with DHT for binding to AR, but also inhibits gonadotropin secretion.
• In one study, Liazal outperformed a drug known as cyproterone acetate, which is sold by Schering AG and other generic manufacturers in Europe.